THE CLINICAL COURSE OF COMORBID SUBSTANCE USE DISORDER AND ATTENTION DEFICIT/HYPERACTIVITY DISORDER: PROTOCOL AND CLINICAL CHARACTERISTICS OF THE INCAS STUDY

Abstract Background Substance use disorders (SUD) often co-occur with attention deficit hyperactivity disorder (ADHD).Although the short-term effects of some specific interventions have been investigated in randomized clinical trials, little is known about the long-term clinical course of treatment-seeking SUD patients with comorbid ADHD.Aims This

This paper quantifies the benefits of flattening Collections the curve (with a constant total patient load over the study period) on the risk of a hospital bed shortage in a pandemic.Using discrete-event simulation of patient care paths in hospitals, synthetic data that eliminates issues of confounding affects from the simultaneous occurrence of re

Background: More than 20,000 people annually develop avascular necrosis (AVN) worldwide, most of whom aged 20 to 50 years, and should refer to orthopedic surgeons for treatment.The quality of life of such patients is low due to chronic pain and sometimes they are deprived of their occupation and social life.Case Report: A 57-year-old Socks male pat

While the United States has had almost fifty years of experience with anticorruption law involving transnational enforcement, Brazilian anticorruption enforcement has not yet celebrated its first decade.In the notorious Car Wash case, however, Brazil is wrestling with the largest anticorruption investigation ever.The Car Wash case has resulted in n

In recent years, research on sphingolipids, particularly ceramides, has attracted increased attention, revealing the important roles and many functions of these molecules in several human neurological disorders.The nervous system is enriched with important classes of sphingolipids, e.g., ceramide and its derivatives, which compose the major portion